A Wide Variety of Applications for Improving Blood Circulation

Poor circulation is a gateway for a litany of ailments: slow healing, depression, poor complexion, sores, slow metabolism, and more.

Rapidly growing supportive evidence suggests that microvascular dysfunction may underlie most chronic disease states.

Our mission started long before the birth of Circularity on March 2011 since the increasing number of patients with diabetes, cardiovascular, and COPD complications is creating an epidemic globally with uncontrollable costs.

Our products can be tested in minutes at the point of care or at home by the most accurate and advanced FDA-cleared non-invasive diagnostics and are being recognized by key opinion and medical thought leaders in the United States and many countries as upcoming breakthrough painless medical technologies.

We promise to change the standard of care, the dynamics of how health care is delivered at health care facilities and at home.

In short, optimized and improved autonomic nervous system and micro-vascular activity is described in published and peer-reviewed scientific research to regenerate fundamental physiological processes, reducing the risk of widespread chronic illnesses, improving sleep, stamina, skin health and beautification.

Circularity is pursuing regulatory approvals in the United States, Europe, Asia and other regions as treatment of various disease states such as chronic wounds for diabetics.

Why Transdermal Delivery?

Your SkinTransdermal delivery is the method of delivering molecules, including CO2, through the skin and directly to the bloodstream.

A rise in demand exists for local transdermal delivery bypassing absorption issues with oral, injection and inhalation deliveries. While the limitation of small molecule sizes and negative side effects leading to skin irritation are plaguing existing transdermal delivery technologies (e.g., microneedles, high velocity fluids, patches, nanoparticles).

Using the transdermal pathway to deliver active molecules through the skin offers many advantages over traditional methods. Clearly, its non-invasiveness makes it a much more patient-friendly method than painful needle-based injections.

Circularity's proprietary transdermal delivery platform via the skin pores, sweat glands and to microcirculation reaching the subcutaneous tissue promises to achieve higher Skin Perfusion Pressure (SPP) levels with lower administered dosages while providing consistent control of skin absorption.

By creating more effective and affordable methods of delivering health care, Circularity is laying the groundwork for an explosion in medical and pharmaceutical research into methods of administering drug therapy by transdermal means in the near future.

Circularity recognizes the body’s incredible ability to provide for its own healing and well-being, and recognizes blood as the delivery system for that ability. With D'OXYVA, Circularity has put the theory that better circulation is the key to better health to the test.

D'OXYVA is targeting increased effectiveness of additional applications including daily creams, emergency ointments, mud-wraps, wound dressings, and a wide array of medications as an adjunct regimen.

In addition, D'OXYVA is an effective and fast standalone solution that promises to help heal, regenerate and repair tissue and other major fundamental physiological processes in the body.

D'OXYVA has zero reports of adverse side effects to date.

Why Microcirculation?

Why Microcirculation?The recognition of the importance of proper microcirculatory function has been growing rapidly in medical research in recent years. The fact is microcirculation in the capillaries is the most important system in the body.

It is the natural cleanser of the body. Waste removal is one of the most important aspects of health, especially, in this toxic-filled environment we live in and breathe in.

Capillaries facilitate exchange of nutrients, gases like oxygen and carbon dioxide, wastes, small proteins, and hormones between the blood and body cells. Capillaries web the entire body and every organ with an estimated average length of about 50,000 miles. The microcirculatory system helps the structure and function of connective tissue and helps clear congestion of lymph, skin and other vital tissues.

Why Autonomic Nervous System?

In short, the two main functions of the Autonomic Nervous System (a division of the peripheral nervous system) are the sympathetic and parasympathetic nerve activities that influence all unconscious processes and internal organs in the body. These are heart rate, digestion, respiratory rate, pupillary response, urination, and sexual arousal.

When something goes wrong in this system, it can cause serious problems, including blood pressure problems, heart problems, trouble with breathing and swallowing, erectile dysfunction in men, and others.

Autonomic functions also include control of respiration, cardiac regulation (the cardiac control center), and vasomotor activity (the vasomotor center). The sympathetic nervous system is often considered the "fight or flight" system, while the parasympathetic nervous system is often considered the "rest and digest" system that promotes calming of the nerves return to regular function, and enhancing digestion.

Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels.

When they affect your breathing or heart function, these disorders can be life-threatening.

Autonomic nervous system disorders can occur alone or as the result of another disease, such as Parkinson's disease, alcoholism and diabetes. Problems can affect either part of the system, as in complex regional pain syndromes, or all of the system. Some types are temporary, but many worsen over time.

Autonomic Nervous System